Similar to spinal cord stimulators (SCS), patients can receive dorsal root ganglion (DRG) stimulators, devices that interfere with pain signaling from the DRG, an easy to reach structure in the spine that contains a large amount of sensory nerves. This device is used to treat pain signaling from areas that are difficult to treat through SCS, such as within the hands, groin, knee, chest, or abdomen.

This method does not eliminate the source of pain but, instead, blocks the sensation so that the patient feels less of it. The device is programmed to provide each patient with settings that are best suited to their condition. In addition, patients are given a remote that they can use to control their DRG stimulator, allowing them to further personalize their settings and receive the most relief possible.

Before a permanent stimulator device is placed in the body, patients are able to trial an external version. The amount of relief provided varies from person to person and, if the trial stimulator is unsuccessful, it can easily be removed and the patient can pursue other forms of treatment.